# Adam Hume Source: https://hello.cv/adamhume ## Work ### Research Assistant Professor | Boston University Medical Campus ### Senior Research Scientist | Boston University Medical Campus: Boston, MA, US ### Research Scientist | Boston University Medical Campus ### Postdoctoral Associate | Boston University Medical Campus ## Education ### University of Wisconsin Madison | PhD ### Bates College | Bachelor of Science ## Publications ### Inhibitors of dihydroorotate dehydrogenase synergize with the broad antiviral activity of 4′-fluorouridine Antiviral Research journal-article ### Harnessing Hazara Virus as a Surrogate for Crimean–Congo Hemorrhagic Fever Virus Enables Inactivation Studies at a Low Biosafety Level Pathogens journal-article ### Harnessing Hazara Virus as a Surrogate for Crimean–Congo Hemorrhagic Fever Virus Enables Inactivation Studies at a Low Biosafety Level Pathogens journal-article ### A Comparative Assessment of the Pathogenic Potential of Newly Discovered Henipaviruses Pathogens journal-article ### Low-Input, High-Resolution 5′ Terminal Filovirus RNA Sequencing with ViBE-Seq Viruses journal-article ### Low-Input, High-Resolution 5′ Terminal Filovirus RNA Sequencing with ViBE-Seq Viruses journal-article ### Improved protein splicing through viral passaging mBio journal-article ### Heat Inactivation of Nipah Virus for Downstream Single-Cell RNA Sequencing Does Not Interfere with Sample Quality Pathogens journal-article ### Heat Inactivation of Nipah Virus for Downstream Single-Cell RNA Sequencing Does Not Interfere with Sample Quality Pathogens journal-article ### A high-throughput, polymerase-targeted RT-PCR for broad detection of mammalian filoviruses Microbiology Spectrum journal-article ### A Comparative Assessment of the Pathogenic Potential of Newly Discovered Henipaviruses Pathogens journal-article ### Art of the Kill: Designing and Testing Viral Inactivation Procedures for Highly Pathogenic Negative Sense RNA Viruses Pathogens journal-article ### Art of the Kill: Designing and Testing Viral Inactivation Procedures for Highly Pathogenic Negative Sense RNA Viruses Pathogens journal-article ### Isolation and genome characterization of Lloviu virus from Italian Schreibers’s bats Scientific Reports journal-article ### Establishment of an Inactivation Method for Ebola Virus and SARS-CoV-2 Suitable for Downstream Sequencing of Low Cell Numbers Pathogens journal-article ### Establishment of an Inactivation Method for Ebola Virus and SARS-CoV-2 Suitable for Downstream Sequencing of Low Cell Numbers Pathogens journal-article ### Minor intron–containing genes as an ancient backbone for viral infection? PNAS Nexus journal-article ### Renaming of genera Ebolavirus and Marburgvirus to Orthoebolavirus and Orthomarburgvirus, respectively, and introduction of binomial species names within family Filoviridae Archives of Virology journal-article ### Ebola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes Stem Cell Reports journal-article ### Ebola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes Stem Cell Reports journal-article ### Labeling Ebola Virus with a Self-Splicing Fluorescent Reporter Microorganisms journal-article ### Labeling Ebola Virus with a Self-Splicing Fluorescent Reporter Microorganisms journal-article ### Author Correction: Isolation of infectious Lloviu virus from Schreiber’s bats in Hungary Nature Communications journal-article ### Author Correction: Isolation of infectious Lloviu virus from Schreiber’s bats in Hungary (Nature Communications, (2022), 13, 1, (1706), 10.1038/s41467-022-29298-1) Nature Communications journal-article ### Author Correction: Isolation of infectious Lloviu virus from Schreiber’s bats in Hungary (Nature Communications, (2022), 13, 1, (1706), 10.1038/s41467-022-29298-1) Nature Communications journal-article ### Isolation of infectious Lloviu virus from Schreiber’s bats in Hungary Nature Communications journal-article ### Isolation of infectious Lloviu virus from Schreiber’s bats in Hungary Nature Communications journal-article ### Isolation of infectious Lloviu virus from Schreiber’s bats in Hungary Nature Communications journal-article ### Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection American Journal of Physiology-Lung Cellular and Molecular Physiology journal-article ### Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection American Journal of Physiology - Lung Cellular and Molecular Physiology journal-article ### Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection American Journal of Physiology - Lung Cellular and Molecular Physiology journal-article ### Recombinant Lloviu virus as a tool to study viral replication and host responses PLOS Pathogens journal-article ### Recombinant Lloviu virus as a tool to study viral replication and host responses PLoS Pathogens journal-article ### Recombinant Lloviu virus as a tool to study viral replication and host responses PLoS Pathogens journal-article ### A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune–epithelial interface Proceedings of the National Academy of Sciences journal-article ### A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune–epithelial interface Proceedings of the National Academy of Sciences of the United States of America journal-article ### A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune–epithelial interface Proceedings of the National Academy of Sciences of the United States of America journal-article ### Erratum: Recombinant Lloviu virus as a tool to study viral replication and host responses (PLoS Pathogens (2022) 18:2 (e1010268) DOI: 10.1371/journal.ppat.1010268) PLoS Pathogens journal-article ### Erratum: Recombinant Lloviu virus as a tool to study viral replication and host responses (PLoS Pathogens (2022) 18:2 (e1010268) DOI: 10.1371/journal.ppat.1010268) PLoS Pathogens journal-article ### Interferon-alpha or -beta facilitates SARS-CoV-2 pulmonary vascular infection by inducing ACE2 Angiogenesis journal-article ### Interferon-alpha or -beta facilitates SARS-CoV-2 pulmonary vascular infection by inducing ACE2 Angiogenesis journal-article ### The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters bioRxiv other ### The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters bioRxiv other ### Isolation and genome characterization of Lloviu virus from Italian Schreibers’ bent-winged bats preprint ### Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection bioRxiv other ### Reservoir host studies of Lloviu virus: first isolation, sequencing and serology in Schreiber’s bats in Europe other ### Reservoir host studies of Lloviu virus: First isolation, sequencing and serology in Schreiber's bats in Europe bioRxiv other ### Reservoir host studies of Lloviu virus: First isolation, sequencing and serology in Schreiber's bats in Europe bioRxiv other ### Recombinant Lloviu virus as a model to study inaccessible zoonotic viruses other ### Recombinant Lloviu virus as a model to study inaccessible zoonotic viruses bioRxiv other ### Recombinant Lloviu virus as a model to study inaccessible zoonotic viruses bioRxiv other ### Human Pluripotent Stem Cell-Derived Intestinal Organoids Model SARS-CoV-2 Infection Revealing a Common Epithelial Inflammatory Response. Stem cell reports journal-article ### Human Pluripotent Stem Cell-Derived Intestinal Organoids Model SARS-CoV-2 Infection Revealing a Common Epithelial Inflammatory Response Stem Cell Reports journal-article ### Human Pluripotent Stem Cell-Derived Intestinal Organoids Model SARS-CoV-2 Infection Revealing a Common Epithelial Inflammatory Response Stem Cell Reports journal-article ### A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV2 at the immune-epithelial interface bioRxiv other ### Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection bioRxiv other ### A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV2 at the immune-epithelial interface bioRxiv other ### Ebola virus infection induces a type I interferon response and the shutdown of key liver functions in human iPSC-derived hepatocytes ResearchSquare other ### Ebola virus infection induces a type I interferon response and the shutdown of key liver functions in human iPSC-derived hepatocytes ResearchSquare other ### Erratum: Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2 (Molecular Cell (2020) 80(6) (1104–1122.e9), (S1097276520308285), (10.1016/j.molcel.2020.11.028)) Molecular Cell journal-article ### Erratum: Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2 (Molecular Cell (2020) 80(6) (1104–1122.e9), (S1097276520308285), (10.1016/j.molcel.2020.11.028)) Molecular Cell journal-article ### Human Pluripotent Stem Cell Derived Intestinal Organoids Model SARS-CoV-2 Infection Revealing a Common Epithelial Inflammatory Response SSRN other ### Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2 Molecular Cell journal-article ### Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2 Molecular Cell journal-article ### Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2 Molecular Cell journal-article ### MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses Science journal-article ### MHC class II transactivator CIITA induces cell resistance to ebola virus and SARS-like coronaviruses Science journal-article ### MHC class II transactivator CIITA induces cell resistance to ebola virus and SARS-like coronaviruses Science journal-article ### SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. Cell stem cell journal-article ### SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response Cell Stem Cell journal-article ### SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response Cell Stem Cell journal-article ### Egyptian Rousette IFN-ω Subtypes Elicit Distinct Antiviral Effects and Transcriptional Responses in Conspecific Cells Frontiers in Immunology journal-article ### Egyptian Rousette IFN-ω Subtypes Elicit Distinct Antiviral Effects and Transcriptional Responses in Conspecific Cells Frontiers in Immunology journal-article ### Egyptian Rousette IFN-ω Subtypes Elicit Distinct Antiviral Effects and Transcriptional Responses in Conspecific Cells Frontiers in Immunology journal-article ### Human Pluripotent Stem Cell Derived Intestinal Organoids Model SARS-CoV-2 Infection Revealing a Common Epithelial Inflammatory Response SSRN other ### Reconstructed signaling and regulatory networks identify potential drugs for SARS-CoV-2 infection bioRxiv other ### Reconstructed signaling and regulatory networks identify potential drugs for SARS-CoV-2 infection bioRxiv other ### SARS-CoV-2 infection of pluripotent stem cell-derived human lung alveolar type 2 cells elicits a rapid epithelial-intrinsic inflammatory response bioRxiv other ### SARS-CoV-2 infection of pluripotent stem cell-derived human lung alveolar type 2 cells elicits a rapid epithelial-intrinsic inflammatory response bioRxiv other ### SARS-CoV-2 spike protein interacts with multiple innate immune receptors bioRxiv other ### SARS-CoV-2 spike protein interacts with multiple innate immune receptors bioRxiv other ### Recent advances in marburgvirus research F1000Research journal-article ### Recent advances in marburgvirus research [version 1; peer review: 3 approved] F1000Research journal-article ### Recent advances in marburgvirus research [version 1; peer review: 3 approved] F1000Research journal-article ### Ebolavirus polymerase uses an unconventional genome replication mechanism. Proceedings of the National Academy of Sciences of the United States of America journal-article ### Ebolavirus polymerase uses an unconventional genome replication mechanism. journal-article ### Ebolavirus polymerase uses an unconventional genome replication mechanism Proceedings of the National Academy of Sciences of the United States of America journal-article ### Ebolavirus polymerase uses an unconventional genome replication mechanism Proceedings of the National Academy of Sciences of the United States of America journal-article ### Distinct Genome Replication and Transcription Strategies within the Growing Filovirus Family Journal of Molecular Biology journal-article ### Distinct Genome Replication and Transcription Strategies within the Growing Filovirus Family Journal of Molecular Biology journal-article ### Distinct Genome Replication and Transcription Strategies within the Growing Filovirus Family Journal of Molecular Biology journal-article ### Recent advances in marburgvirus research [version 1; peer review: 3 approved] journal-article ### Marburg Virus Viral Protein 35 Inhibits Protein Kinase R Activation in a Cell Type-Specific Manner. journal-article ### Marburg Virus Viral Protein 35 Inhibits Protein Kinase R Activation in a Cell Type-Specific Manner Journal of Infectious Diseases journal-article ### Marburg Virus Viral Protein 35 Inhibits Protein Kinase R Activation in a Cell Type-Specific Manner Journal of Infectious Diseases journal-article ### The Egyptian Rousette Genome Reveals Unexpected Features of Bat Antiviral Immunity. Cell journal-article ### The Egyptian Rousette Genome Reveals Unexpected Features of Bat Antiviral Immunity Cell journal-article ### The Egyptian Rousette Genome Reveals Unexpected Features of Bat Antiviral Immunity. journal-article ### Toll-like receptor 4 in acute viral infection: Too much of a good thing. PLoS pathogens journal-article ### Toll-like receptor 4 in acute viral infection: Too much of a good thing. journal-article ### Toll-like receptor 4 in acute viral infection: Too much of a good thing PLoS Pathogens journal-article ### Toll-like receptor 4 in acute viral infection: Too much of a good thing PLoS Pathogens journal-article ### A Chimeric Lloviu Virus Minigenome System Reveals that the Bat-Derived Filovirus Replicates More Similarly to Ebolaviruses than Marburgviruses. Cell reports journal-article ### A Chimeric Lloviu Virus Minigenome System Reveals that the Bat-Derived Filovirus Replicates More Similarly to Ebolaviruses than Marburgviruses. journal-article ### A Chimeric Lloviu Virus Minigenome System Reveals that the Bat-Derived Filovirus Replicates More Similarly to Ebolaviruses than Marburgviruses Cell Reports journal-article ### A Chimeric Lloviu Virus Minigenome System Reveals that the Bat-Derived Filovirus Replicates More Similarly to Ebolaviruses than Marburgviruses Cell Reports journal-article ### The Egyptian Rousette Genome Reveals Unexpected Features of Bat Antiviral Immunity Cell journal-article ### Marburg Virus Viral Protein 35 Inhibits Protein Kinase R Activation in a Cell Type-Specific Manner. The Journal of infectious diseases journal-article ### Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Responses in Human Macrophages. journal-article ### An RNA polymerase II-driven Ebola virus minigenome system as an advanced tool for antiviral drug screening. Antiviral research journal-article ### An RNA polymerase II-driven Ebola virus minigenome system as an advanced tool for antiviral drug screening. journal-article ### An RNA polymerase II-driven Ebola virus minigenome system as an advanced tool for antiviral drug screening Antiviral Research journal-article ### An RNA polymerase II-driven Ebola virus minigenome system as an advanced tool for antiviral drug screening Antiviral Research journal-article ### Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Responses in Human Macrophages. Journal of virology journal-article ### Ebolaviruses associated with differential pathogenicity induce distinct host responses in human macrophages Journal of Virology journal-article ### Ebolaviruses associated with differential pathogenicity induce distinct host responses in human macrophages Journal of Virology journal-article ### Filovirus Strategies to Escape Antiviral Responses. Current topics in microbiology and immunology journal-article ### Filovirus Strategies to Escape Antiviral Responses. journal-article ### Filovirus strategies to escape antiviral responses Current Topics in Microbiology and Immunology book-chapter ### Filovirus strategies to escape antiviral responses Current Topics in Microbiology and Immunology book-chapter ### Inactivation of RNA viruses by gamma irradiation: A study on mitigating factors Viruses journal-article ### Inactivation of RNA viruses by gamma irradiation: A study on mitigating factors Viruses journal-article ### Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions. journal-article ### Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions Journal of Virology journal-article ### Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions Journal of Virology journal-article ### Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions. Journal of virology journal-article ### Inactivation of RNA Viruses by Gamma Irradiation: A Study on Mitigating Factors. Viruses journal-article ### Inactivation of RNA Viruses by Gamma Irradiation: A Study on Mitigating Factors. journal-article ### Forty-Five Years of Marburg Virus Research Viruses journal-article ### Forty-five years of marburg virus research Viruses journal-article ### Forty-five years of Marburg virus research. Viruses journal-article ### Forty-five years of Marburg virus research. journal-article ### Forty-five years of marburg virus research Viruses journal-article ### Regulation of the retinoblastoma proteins by the human herpesviruses Cell Division journal-article ### Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human cytomegalovirus lacking UL97 protein kinase. Proceedings of the National Academy of Sciences of the United States of America journal-article ### Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human cytomegalovirus lacking UL97 protein kinase. journal-article ### Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human cytomegalovirus lacking UL97 protein kinase Proceedings of the National Academy of Sciences of the United States of America journal-article ### Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human cytomegalovirus lacking UL97 protein kinase Proceedings of the National Academy of Sciences of the United States of America journal-article ### Regulation of the retinoblastoma proteins by the human herpesviruses. Cell division journal-article ### Regulation of the retinoblastoma proteins by the human herpesviruses. journal-article ### Regulation of the retinoblastoma proteins by the human herpesviruses Cell Division journal-article ### Phosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function Science journal-article ### Phosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function. Science (New York, N.Y.) journal-article ### Phosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function. journal-article ### Phosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function Science journal-article ### Early developmental 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure decreases chick embryo heart chronotropic response to isoproterenol but not to agents affecting signals downstream of the beta-adrenergic receptor Toxicological Sciences journal-article ### Early developmental 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure decreases chick embryo heart chronotropic response to isoproterenol but not to agents affecting signals downstream of the beta-adrenergic receptor Toxicological Sciences journal-article ### Early developmental 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure decreases chick embryo heart chronotropic response to isoproterenol but not to agents affecting signals downstream of the beta-adrenergic receptor. Toxicological Sciences journal-article ### Early developmental 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure decreases chick embryo heart chronotropic response to isoproterenol but not to agents affecting signals downstream of the beta-adrenergic receptor. journal-article ## Source Read this profile on Hello.cv: https://hello.cv/adamhume Create your free profile at https://hello.cv